Rutoside (also known as rutin, quercetin-3-O-rutinoside or sophorin) is a flavonoid glycoside composed of the flavonol quercetin and the disaccharide rutinose (α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranose).It occurs naturally in many plants, particularly in citrus fruits.
Rutoside has anticoagulant (blood-thinning) properties and plays an important role in wound healing, as well as in the reduction of bruising and swelling.At higher doses, it prevents the deformation of red blood cells and reduces the aggregation (clumping) of platelets — an essential mechanism of protection, as clumped platelets may form life-threatening clots that could block a vessel in the lungs, causing hypoxia or even death.
Rutoside also improves venous and lymphatic circulation, especially in the lower extremities.
As a potent antioxidant, it protects the fatty acids in cell membranes, helping to slow down the skin’s aging process, and can reduce the appearance of fine lines and stretch marks.
Rutoside is frequently combined with vitamin C (L-ascorbic acid) – and for good reason:These two compounds enhance each other’s effects. Rutoside protects vitamin C from oxidation and improves its absorption and stability in the body.Vitamin C, on the other hand, supports immune function and helps create an acidic environment in which viruses have a harder time multiplying.
Together, rutoside and vitamin C are significantly more effective than either used alone.This combination is especially recommended for recurrent infections or vitamin C deficiency, even in children.
What matters most is the correct ratio of the two compounds — as neither is as effective on its own.
https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cmdc.202200157
https://link.springer.com/article/10.1007/s00403-019-01898-w